OIV INFEKTSIYASILI O'TKIR DIAREYA BILAN OG'RIGAN BOLALARDA LIPID SPEKTRI KO'RSATKICHLARINI QIYOSIY BAHOLASH
Abstract
Diareya kasalliklari past va o‘rta daromadli mamlakatlarda yashovchi bolalarda kasallanish va o‘limning ikki asosiy sababi hisoblanadi [1]. Gaiti hududida o‘tkazilgan milliy vakillik tadqiqotiga ko‘ra, so‘nggi 2 hafta ichida 6–11 oylik chaqaloqlarning taxminan 38% diareya kasalligini boshdan kechirgan [3]. Takrorlanuvchi diareya kasalliklari ko‘pincha yetarlicha oziqlanishni yomonlashtiradi va yashirin energiya va oziq moddalari tanqisligini kuchaytirishi mumkin [4]. Ushbu qaytariluvchi diareya kasalliklari va yomonlashayotgan oziqlanish sikli ekologik enternal disfunktsiya (EED) deb ataladigan, ingichka ichakning subklinik buzilishi bilan tavsiflanadigan, kiprikchalarning yupqalashishi va kriptalarning giperplaziyasi holatiga olib kelishi mumkin [6]. OIV infeksiyasi bilan og‘rigan bolalarda, ayniqsa yengil diareyaga duch kelganlarda, lipid almashinuvi bir nechta omillar ta’sirida buzilishi mumkin: immunitetning zaiflashishi, virus infeksiyasining o‘zi ta’siri va/yoki antiretrovirus terapiyasining kuchli ta’sirlari. Bunday bemorlar orasida lipid fenomenini baholash diagnostika va holatni monitoring qilishda, shuningdek profilaktika yoki jarrohlik amaliyotlarini o‘tkazishda yordam berishi mumkin [2].
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